| Gene Symbol | UBB |
| Full Name | Ubiquitin B |
| Aliases | UBBPROTEIN |
| Protein Type | Ligase |
| Function | UBB produces polyubiquitin chains that are processed into单体 ubiquitin |
| Subcellular Localization | </th><td>Cytoplasm, Nucleus, All Cellular Compartments</td></tr> |
| Pathways | Mitophagy |
| Ensembl ID | ENSG00000104140 |
| GeneCards | UBB |
| Human Protein Atlas | UBB |
| Proteasomal degradation | K48-linked polyubiquitin chains tag proteins for 26S proteasome<sup>[1]</sup> |
| [Autophagy](/entities/autophagy) | K63-linked chains for selective autophagy |
| Endocytosis | Monoubiquitination for receptor downregulation |
| DNA repair | Ubiquitin for histone modification and repair |
| Quality control | Targets misfolded/damaged proteins |
| Associated Diseases | neurodegeneration |
| KG Connections | 17 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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