| Gene Symbol | U2AF2 |
| Aliases | U2AF2PROTEIN |
| Chromosome | 19q13.42 |
| Function | is a core spliceosomal protein essential for the recognition of the 3' splice site during pre-mRNA splicing. |
| Subcellular Localization | </strong></td><td>Nucleus (spliceosome)</td></tr> |
| Molecular Weight | 65kDa |
| Amino Acids | 475 aa |
| Pathways | pathway: **Assembly Sequence:** |
| Ensembl ID | ENSG00000163251 |
| GeneCards | U2AF2 |
| Human Protein Atlas | U2AF2 |
| N-terminal RS Domain | Arginine/serine-rich region for protein-protein interactions with splicing cofactors |
| RRM1 and RRM2 | Two RNA recognition motifs that bind the polypyrimidine tract and 3' splice site |
| C-terminal U2AF Homology Motif (UHM) | Mediates interaction with U2AF1 (U2AF35) |
| Synaptic Proteins | NMDA receptor subunits, AMPA receptor auxiliary subunits |
| Associated Diseases | Als, Ms |
| KG Connections | 4 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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