| Gene Symbol | TTTRPROTEIN |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | </th><td>Secreted, extracellular</td></tr> |
| Molecular Weight | 14 kDa |
| GeneCards | TTTRPROTEIN |
| Human Protein Atlas | TTTRPROTEIN |
| Thyroid hormone transport | Carries thyroxine (T4) in plasma and CSF |
| Retinol transport | Binds retinol-binding protein (RBP) to deliver vitamin A |
| Extracellular protein homeostasis | Acts as a "molecular chaperone" |
| Autosomal dominant | Caused by TTR gene mutations |
| Familial amyloid polyneuropathy (FAP) | Peripheral neuropathy, autonomic dysfunction |
| Familial amyloid cardiomyopathy (FAC) | Cardiac amyloidosis |
| Leptomeningeal amyloidosis | CNS involvement |
| Age-related | Wild-type TTR forms amyloid with age |
| Predominantly cardiac | Deposits in heart |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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