| Gene Symbol | TPPPPROTEIN |
| Function | is a 219 amino acid intrinsically disordered protein that stabilizes microtubules and promotes tubulin acetylation in oligodendrocytes. |
| Subcellular Localization | </td><td>Cytoplasm (perinuclear, cell processes in oligodendrocytes)</td></tr> |
| Molecular Weight | 24 kDa |
| GeneCards | TPPPPROTEIN |
| Human Protein Atlas | TPPPPROTEIN |
| GTPase active site | The Walker A motif (GxxxxGK) and Walker B motif (DxxG) enable GTP hydrolysis with Km ~ 30 μM, similar to small GTPases |
| TPPP2 | Testis-specific |
| TPPP3/p20 | Broader tissue expression, ciliary function |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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