protein 627 words KG: TOMM22PROTEIN
Contents

TOMM22 — Translocase of Outer Mitochondrial Membrane 22

🔬 Protein Info
Gene SymbolTOMM22
Full NameTranslocase of Outer Mitochondrial Membrane 22
AliasesTOMM22PROTEIN
FunctionTOMM22 (Translocase of Outer Mitochondrial Membrane 22 kDa) is a critical receptor subunit of the TOM (Translocase of Outer Membrane) complex that mediates protein import into mitochondria.
Molecular Weight22 kDa
GeneCardsTOMM22
Human Protein AtlasTOMM22
TOM ComplexParent translocase machinery
TOMM20Primary receptor component
TOMM40Channel-forming protein
HSP90/HSP70Cooperating chaperones
Mitochondrial Targeting SequencesRecognized substrate motifs
Mitochondrial Protein ImportCore biological process
Oxidative PhosphorylationDependent process
Neuronal BioenergeticsDownstream biological outcome
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Related Hypotheses (17)

AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.82
Senescent Cell Mitochondrial DNA Release
Score: 0.74
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.74
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73
Membrane Cholesterol Gradient Modulators
Score: 0.71
Mitochondrial Transfer Pathway Enhancement
Score: 0.70
CX43 hemichannel engineering enables size-selective mitochon
Score: 0.69
RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.67
Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.67
GAP43-mediated tunneling nanotube stabilization enhances neu
Score: 0.67
Mitochondrial RNA Granule Rescue Pathway
Score: 0.66
Mitochondrial Calcium Buffering Enhancement via MCU Modulati
Score: 0.65
Mitochondrial SPM Synthesis Platform Engineering
Score: 0.65
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
Lysosomal Membrane Repair Enhancement
Score: 0.54

Related Analyses (14)

Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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