| Gene Symbol | TIA1L |
| Full Name | TIA1L (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like) |
| Aliases | TIA-1 Like Protein |
| Chromosome | 19p13.3 |
| Protein Type | Gene |
| Function | is a member of the TIA family of RNA binding proteins that plays critical roles in post-transcriptional gene regulation, stress granule assembly, and RNA metabolism. |
| Primary Expression | the brain, particularly in neurons of the cortex, hippocampus, and basal ganglia, where it participates in translational control and stress response p |
| Molecular Weight | 45 kDa |
| Amino Acids | 420 aa |
| Ensembl ID | ENSG00000134827 |
| GeneCards | TIA1L |
| Human Protein Atlas | TIA1L |
| RRM1 (residues 82-161) | Primary RNA-binding domain with high affinity for U-rich sequences |
| RRM2 (residues 162-243) | Contributes to RNA binding specificity |
| RRM3 (residues 244-325) | May be involved in protein-protein interactions |
| Associated Diseases | Alzheimer's disease, Parkinson's disease, ALS |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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