| Gene Symbol | RGS3 |
| Full Name | Regulator of G Protein Signaling 3 |
| Aliases | RGS3PROTEIN |
| Function | Regulator of G protein Signaling 3 (RGS3) is a member of the RGS protein family, which function as GTPase-activating proteins (GAPs) for heterotrimeric G proteins. |
| Primary Expression | a tissue-specific manner |
| Subcellular Localization | </strong></td><td>Cytoplasm, membrane</td></tr> |
| Molecular Weight | 60 kDa |
| Amino Acids | 120 aa |
| Ensembl ID | ENSG00000138835 |
| GeneCards | RGS3 |
| Human Protein Atlas | RGS3 |
| RGS Domain | The conserved catalytic core (~120 amino acids) that confers GAP activity |
| N-terminal Region | Contains regulatory sequences that modulate protein localization and interactions |
| PDZ-binding Motif | Allows interaction with PDZ domain-containing proteins |
| Dopaminergic Signaling | Regulates D2 dopamine receptor signaling in striatum [1] |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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