| Gene Symbol | RGS12 |
| Aliases | Regulator of G Protein Signaling 12 |
| Chromosome | 10q26.3 |
| Protein Type | Gene |
| Function | is a member of the RGS protein family that plays critical roles in modulating G protein-coupled receptor (GPCR) signaling in neurons. |
| Subcellular Localization | includes the synapse, dendrite, cytoplasm, and nucleus, enabling it to modulate both rapid synaptic signaling and longer |
| Amino Acids | 447 aa |
| GeneCards | RGS12 |
| Human Protein Atlas | RGS12 |
| Synaptic transmission | RGS12 modulates neurotransmitter release by controlling Gαi/o signaling at presynaptic terminals |
| Receptor desensitization | Rapid GAP activity terminates receptor signaling, enabling dynamic responses to repeated stimuli |
| Signal integration | By interacting with multiple receptor types, RGS12 coordinates signaling from different neurotransmitters |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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