protein 1,123 words KG: RASGEF1APROTEIN
Contents

RASGEF1A Protein

🔬 Protein Info
Gene SymbolRASGEF1A
Full NameRasGEF Domain Family Member 1A
AliasesRASGEF1APROTEIN
Chromosome10q21.3
FunctionThis activity is essential for
Primary Expressionvarious tissues, with particular abundance in brain, and plays important roles in neuronal function and development
Subcellular LocalizationCytoplasm, with translocation to membranes upon activation
Molecular WeightApproximately 90-100 kDa
Pathwaysmapk, MAPK signaling, MAPK Signaling, MAPK
UniProt ID[Q8IUR5](https://www.uniprot.org/uniprot/Q8IUR5)
Ensembl IDENSG00000165682
GeneCardsRASGEF1A
Human Protein AtlasRASGEF1A
IsoformsMultiple isoforms generated through alternative splicing
RasGEF DomainThe catalytic domain responsible for GDP/GTP exchange activity on Ras proteins
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

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