| Gene Symbol | RAB5A |
| Full Name | Ras-Related Protein Rab-5A |
| Aliases | RAB5APROTEIN |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | </strong></td><td>Early endosomes, cytoplasmic vesicles, presynaptic terminals</td></tr> |
| Molecular Weight | 24 kDa |
| Amino Acids | 218 aa |
| Pathways | MAPK signaling |
| Ensembl ID | ENSG00000108510 |
| GeneCards | RAB5A |
| Human Protein Atlas | RAB5A |
| N-terminal region | Contains the Switch I region that undergoes conformational changes between GTP/GDP states |
| Nucleotide-binding pocket | High-affinity binding site for GDP/GTP |
| C-terminal hypervariable region | Determines subcellular localization |
| CAAX motif | Undergoes geranylgeranylation for membrane anchoring |
| Associated Diseases | Als |
| Interactions | NEURODEGENERATIVE DISEASES |
| KG Connections | 30 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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