| Gene Symbol | RAB25 |
| Aliases | RAB25PROTEIN |
| Chromosome | 1q22. |
| Protein Type | Gene |
| Function | is a gene/protein involved in various cellular processes relevant to neurodegenerative diseases. |
| Primary Expression | various tissues with highest expression in: - Kidney (high expression in tubular epithelial cells) - Liver (hepatocytes) - Brain (moderate expression |
| Subcellular Localization | </th><td>Endosomes, Lysosomes, Plasma Membrane</td></tr> |
| Molecular Weight | 24 kDa |
| Amino Acids | 219 aa |
| Exons | 7 |
| GeneCards | RAB25 |
| Human Protein Atlas | RAB25 |
| GTP-binding domain (G domain) | Approximately 170 residues forming a Rossmann-fold structure that binds GTP/Mg²⁺ |
| Switch regions I and II | Conformational changes between GTP- and GDP-bound states (~20 residues each) |
| Hypervariable C-terminal region | Determines effector specificity and subcellular targeting |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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