protein 1,309 words KG: PTPRDPROTEIN
Contents

PTPRD Protein

🔬 Protein Info
Gene SymbolPTPRD
AliasesPTPRDPROTEIN
FunctionPTPRD is highly expressed in the nervous system, particularly in the cerebral cortex, hippocampus, cerebellum, and spinal cord.
Subcellular Localization</strong></td><td>Cell membrane, Postsynaptic density</td></tr>
Molecular Weight220 kDa
Amino Acids1917 aa
GeneCardsPTPRD
Human Protein AtlasPTPRD
Ig-like DomainMediates protein-protein interactions
Fibronectin Type III RepeatsProvide structural support and interaction surfaces
Single Transmembrane HelixSpans the plasma membrane
D1 Phosphatase DomainThe major catalytic domain with phosphatase activity
D2 Phosphatase DomainA second, less active phosphatase domain that may regulate D1 activity
DimerizationPTPRD can form homodimers through extracellular interactions, which may regulate phosphatase activity
Ligand BindingVarious extracellular ligands modulate PTPRD function
InteractionsPTPRF
KG Connections2 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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