protein 656 words KG: PMCA1PROTEIN
Contents

PMCA1 Protein — Plasma Membrane Calcium ATPase 1

🔬 Protein Info
Gene SymbolPMCA1PROTEIN
AliasesPMCA1PROTEIN
Chromosome12q21.33
Subcellular Localizations, allowing tissue-specific regulation of calcium extrusion. The protein localizes to the plasma membrane throughout the
ATP2B2, ATP2B3, ATP2B4Other PMCA isoforms with distinct tissue distributions
CalmodulinRegulatory protein essential for PMCA1 activation
NCX1Sodium-calcium exchanger providing alternative calcium extrusion mechanism
CalpainDownstream effector of calcium toxicity
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (7)

Membrane Cholesterol Gradient Modulators
Score: 0.71
Lysosomal Calcium Channel Modulation Therapy
Score: 0.70
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.67
Mitochondrial Calcium Buffering Enhancement via MCU Modulati
Score: 0.65
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62

Related Analyses (9)

Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (2)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40
Synaptic Mitochondrial Resilience Enhancement for Parkinson'
validation · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)