| Gene Symbol | PGAP2 |
| Full Name | Post-GPI Attachment to Proteins 2 |
| Aliases | PGAP2PROTEIN |
| Protein Family | PGAP (Post-GPI Attachment to Proteins) family |
| Protein Type | Enzyme |
| Function | encodes an essential enzyme involved in the remodeling of glycosylphosphatidylinositol (GPI) anchors after their attachment to proteins in the endoplasmic reticulum. |
| Molecular Weight | 40 kDa |
| Ensembl ID | ENSG00000132581 |
| GeneCards | PGAP2 |
| Human Protein Atlas | PGAP2 |
| Molecular weight | ~40 kDa |
| Cellular localization | Endoplasmic reticulum membrane |
| Topology | Multi-pass transmembrane with cytosolic and luminal domains |
| Prion protein (PrP^SC) | GPI-anchored and implicated in Creutzfeldt-Jakob disease |
| Contactins | Critical for neuronal migration and synaptic formation |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!