| Gene Symbol | PDE4A |
| Full Name | Phosphodiesterase 4A |
| Aliases | PDE4APROTEIN |
| Function | PDE4A encodes a cAMP-specific phosphodiesterase belonging to the PDE4 family |
| Subcellular Localization | ** | Cytosol, membrane | |
| UniProt ID | P27815 |
| Ensembl ID | ENSG00000065989 |
| GeneCards | PDE4A |
| Human Protein Atlas | PDE4A |
| N-terminal region | Isoform-specific, determines localization |
| Upstream conserved region (UCR) | Regulatory domain |
| Catalytic domain | C-terminal hydrolase domain |
| cAMP → AMP | Termination of cAMP signaling |
| Compartmentalization | Targeted to specific cellular domains |
| Protein interactions | Binds to AKAPs, mTOR, ERK |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
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