| Gene Symbol | P00519 |
| Aliases | ABL1 non-receptor tyrosine kinase |
| Chromosome | 9q34. |
| Protein Family | Tyrosine Kinase (non-receptor) |
| Protein Type | Receptor |
| Function | It promotes actin polymerization and stress fiber formation through interactions with various cytoskeletal proteins. |
| Primary Expression | Ubiquitous, high in brain |
| Subcellular Localization | Cytoplasm, nucleus |
| Molecular Weight | 120 kDa |
| UniProt ID | [P00519](https://www.uniprot.org/uniprot/P00519) |
| GeneCards | P00519 |
| Human Protein Atlas | P00519 |
| Proline-Rich Region (PRD) | Contains binding sites for SH3-containing proteins |
| F-Actin Binding Domain (FABD) | Enables ABL1 to bind to actin cytoskeleton |
| Nuclear Localization Signal (NLS) | Directs ABL1 to the nucleus |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
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