| Gene Symbol | NRTNPROTEIN |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | ** | Secreted (extracellular) | |
| Molecular Weight | 10 kDa |
| GeneCards | NRTNPROTEIN |
| Human Protein Atlas | NRTNPROTEIN |
| Dopaminergic neuron survival | Promotes SNpc dopaminergic neuron survival |
| Motor neuron protection | Supports motor neuron survival and function |
| Enteric neuron development | Essential for enteric nervous system development |
| Synaptic plasticity | Modulates synaptic function |
| Neuroprotection | Protects dopaminergic neurons from toxin-induced death |
| Synaptic maintenance | Supports synaptic function in the striatum |
| Clinical trials | AAV2-NRTN (CERE-120) tested in PD patients |
| Biomarker potential | NRTN levels as indicator of disease progression |
| ALS | Motor neuron protective effects in models |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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