| Gene Symbol | NOXO1 |
| Full Name | NADPH Oxidase Organizer 1 |
| Function | is a protein encoded by the NOXO1 gene that ### NOX1 Complex Organization |
| Molecular Weight | 41.1 kDa |
| Amino Acids | 366 aa |
| UniProt ID | [Q8NFA2](https://www.uniprot.org/uniprotkb/Q8NFA2) |
| GeneCards | NOXO1 |
| Human Protein Atlas | NOXO1 |
| Proline-rich regions | Mediate binding to NOXA1 |
| PB1 domain | Similar to p47phox but constitutively active |
| Oxidative stress | NOXO1/NOX1 contributes to AD oxidative damage |
| [Tau](/proteins/tau) phosphorylation | ROS from NOX1 affects kinase/phosphatase balance |
| Dopaminergic vulnerability | ROS from NOX1 may damage dopaminergic neurons |
| Neuroinflammation | Contributes to microglial ROS production |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
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