protein 654 words KG: NMDARECEPTORPROTEIN
Contents

NMDA Receptor Protein

🔬 Protein Info
Gene SymbolNMDARECEPTOR
Full NameNMDA Receptor
AliasesNMDARECEPTORPROTEIN
Protein TypeProtein
Functionis a ionotropic glutamate receptor that plays a critical role in synaptic plasticity, learning, and memory.
Primary Expressionmotor neurons and subpopulations of interneurons
Subcellular Localization</td><td>Postsynaptic density, dendritic spines</td></tr>
UniProt IDSearch UniProt
GeneCardsNMDARECEPTOR
Human Protein AtlasNMDARECEPTOR
GluN3A-B subunitsModulatory subunits
C-terminal intracellular domainsRegulate trafficking, scaffolding, and signaling
Polyamine blockMagnesium block requires depolarization to relieve
Excitatory transmissionMajor contributor to excitatory postsynaptic currents
Calcium influxHighly permeable to Ca2+ (unlike AMPA receptors)
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (5)

Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.84
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.67
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (9)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (4)

Ketamine in pediatric TRD patients
clinical · proposed · Score: 0.70
Ketamine in obstetric TRD patients
clinical · proposed · Score: 0.70
Ketamine efficacy in geriatric TRD patients
clinical · proposed · Score: 0.70
Experiment: Autoimmune Hypothesis Testing in AD
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)