| Gene Symbol | MEKK1 |
| Aliases | MAP3K1 |
| Chromosome | 5q11.2 |
| Protein Family | MAP3K serine/threonine kinases |
| Protein Type | Kinase |
| Function | This activation leads to phosphorylation of JNK isoforms, which then phosphorylate transcription factors including c-Jun, driving expression of genes involved in stress response, cell cycle regulation |
| Molecular Weight | 164.3 kDa |
| Amino Acids | 413 aa |
| Pathways | MAPK, MAPK Pathway |
| UniProt ID | [Q13233](https://www.uniprot.org/uniprot/Q13233) |
| GeneCards | MEKK1 |
| Human Protein Atlas | MEKK1 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
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