protein 775 words KG: MBD6PROTEIN
Contents

MBD6 Protein - Methyl-CpG Binding Domain Protein 6

🔬 Protein Info
Gene SymbolMBD6
Full NameMethyl-CpG Binding Domain Protein 6
AliasesPage for MBD6 Gene, Page for MBD6 Protein
Chromosome12q24.31
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionvarious tissues: - Brain: Highest expression in cortex, hippocampus, and cerebellum - Liv
Molecular Weight74 kDa
Amino Acids677 aa
Exons15
UniProt IDQ9Y5W5
NCBI Gene ID79745
Ensembl IDENSG00000166206
GeneCardsMBD6
Human Protein AtlasMBD6
Methyl-CpG binding domain (MBD)A ~80 amino acid domain that recognizes methylated CpG dinucleotides
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

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Related Hypotheses (11)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.38
DNMT1-Targeting Antisense Oligonucleotide Reset
Score: 0.65
Competitive APOE4 Domain Stabilization Peptides
Score: 0.78
Dual-Domain Antibodies with Engineered Fc-FcRn Affinity Modu
Score: 0.77
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73
Interfacial Lipid Mimetics to Disrupt Domain Interaction
Score: 0.72
Glycine-Rich Domain Competitive Inhibition
Score: 0.64
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
Low Complexity Domain Cross-Linking Inhibition
Score: 0.62

Related Analyses (10)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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