| Gene Symbol | MAP4 |
| Aliases | MAP4PROTEIN |
| Chromosome | 3p21.31 |
| Protein Type | Gene |
| Function | Microtubule-associated protein 4 (MAP4) is a cytoskeletal protein that binds to microtubules and regulates their stability, dynamics, and interaction with other cellular components. |
| Primary Expression | non-neuronal cells but is also present in neurons where it interacts with tubulin to promote microtubule assembly and protect aga |
| Subcellular Localization | </td><td>Cytoskeleton, Axons, Dendrites</td></tr> |
| Molecular Weight | 210 kDa |
| Amino Acids | 1862 aa |
| UniProt ID | P27816 |
| GeneCards | MAP4 |
| Human Protein Atlas | MAP4 |
| Prevents depolymerization | Binds along microtubule length, stabilizing protofilaments |
| Promotes polymerization | Facilitates tubulin assembly into microtubules |
| Regulates dynamics | Modifies microtubule instability |
| Associated Diseases | neurodegeneration |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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