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protein 1,505 words KG: LDLRAD3PROTEIN
Contents

LDLRAD3 (LDLR Adapter Protein 1) Protein

🔬 Protein Info
Gene SymbolLDLRAD3
AliasesLDLRAD3PROTEIN
Chromosome1p31.3
Protein FamilyLDLR adapter family
FunctionThe LDLRAD family consists of LDLRAD1, LDLRAD2, LDLRAD3, and LDLRAD4, each with distinct expression patterns and functions.
Subcellular Localization** | Cell membrane, Cytoplasm |
Molecular Weight~47 kDa (407 amino acids)
UniProt IDQ8IY81
GeneCardsLDLRAD3
Human Protein AtlasLDLRAD3
DatabasesGeneCardsNCBI GeneHPASTRING

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UniProtWikipedia

Related Hypotheses (15)

Cholesterol-CRISPR Convergence Therapy for Neurodegeneration
Score: 0.62Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.76APOE Isoform Conversion Therapy
Score: 0.72Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.72Membrane Cholesterol Gradient Modulators
Score: 0.71Competitive APOE4 Domain Stabilization Peptides
Score: 0.78Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.76APOE Isoform Expression Across Glial Subtypes
Score: 0.74APOE4-Selective Lipid Nanoemulsion Therapy
Score: 0.74Interfacial Lipid Mimetics to Disrupt Domain Interaction
Score: 0.72Palmitoylation-Targeted BACE1 Trafficking Disruptors
Score: 0.69Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (9)

CRISPR-based therapeutic approaches for neurodegenerative di
neurodegeneration · archivedBlood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archivedMitochondrial transfer between astrocytes and neurons
neurodegeneration · archivedLipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completedRNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed

Related Experiments (4)

AD Amyloid-Resilient Phenotype Study — Why Some amyloid-Posi
clinical · proposed · Score: 0.40AD Combination Therapy Trial: Anti-Aβ + Anti-Tau
clinical · proposed · Score: 0.40ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40Sex Differences in Alzheimer's Disease — mechanisms and ther
clinical · proposed · Score: 0.40

See Also (15)

Neurodegeneration
disease · KG edge: implicated_inLX1001 Phase 1/2 Trial (NCT03634007) - Gene Therapy for
clinical · Pages share 5 hypothesesALA-enriched Nutrition for APOE4 Carriers with MCI (NCT
clinical · Pages share 5 hypothesesExtracellular Vesicle and Tunneling Nanotube-Mediated S
mechanism · Pages share 5 hypothesesBEACoN Study - Biomarker Exploration in Aging, Cognitio
clinical · Pages share 5 hypotheses

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