protein 769 words KG: LAPTM5PROTEIN
Contents

LAPTM5 Protein

🔬 Protein Info
Gene SymbolLAPTM5
Full NameLysosomal associated transmembrane protein 5
AliasesLAPTM5PROTEIN
Chromosome1p35.1
FunctionThe protein interacts with components of the lysosomal trafficking machinery, including
Subcellular Localization</b></td><td>Lysosome, endoplasmic reticulum</td></tr>
Amino Acids397 aa
UniProt ID[Q9Y5W7](https://www.uniprot.org/uniprot/Q9Y5W7)
Ensembl IDENSG00000125351
GeneCardsLAPTM5
Human Protein AtlasLAPTM5
N-terminal cytoplasmic domainContains sorting motifs for lysosomal targeting
Transmembrane regionsFour transmembrane helices that anchor the protein in the membrane
C-terminal domainInvolved in interactions with autophagy machinery
Autophagosome-lysosome fusionLAPTM5 facilitates the final step of autophagy by promoting membrane fusion events
Associated DiseasesNeurodegeneration, ALS through:
DatabasesGeneCardsNCBI GeneHPASTRING

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