protein 3,781 words KG: KV73PROTEIN
Contents

Kv7.3 Potassium Channel

🔬 Protein Info
Gene SymbolKV73PROTEIN
Full NamePotassium voltage-gated channel subfamily Q member 3
Protein FamilyVoltage-gated potassium channel (KCNQ) family
Protein TypeChannel
Functionis a voltage-gated potassium channel subunit that plays a critical role in regulating neuronal excitability.
Primary Expressionthe central nervous system, where they form heterotetrameric channels that produce the M-current, named for its inhibition by muscarinic agonists
Molecular Weight90 kDa
Amino Acids400 aa
UniProt IDO43525
GeneCardsKV73PROTEIN
Human Protein AtlasKV73PROTEIN
S1-S4Voltage-sensing domain that detects changes in membrane potential
S5-S6Pore-forming domain that conducts potassium ions
N-terminusCytoplasmic domain involved in subunit assembly and modulation
C-terminusLarge cytoplasmic domain (≈400 residues) containing sites for regulation
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

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