| Gene Symbol | HOXA1 |
| Chromosome | 7p15.2 |
| Protein Family | Homeobox family, HoxA cluster |
| Protein Type | Transcription Factor |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | neural stem cells of the subventricular zone - Neuronal Plasticity: May regulate experience-dependent gene expression - Circuit Maintenance: I |
| Subcellular Localization | Nucleus |
| Molecular Weight | 37.3 kDa |
| Amino Acids | 355 aa |
| Pathways | Modulates Wnt, BMP, and FGF signaling |
| UniProt ID | [P49639](https://www.uniprot.org/uniprot/P49639) |
| GeneCards | HOXA1 |
| Human Protein Atlas | HOXA1 |
| Homeodomain | 60-amino acid DNA-binding helix-turn-helix motif |
| N-terminal Transactivation Domain | Contains acidic residues for transcriptional activation |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
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