protein 951 words KG: HMOX2PROTEIN
Contents

Heme Oxygenase 2

🔬 Protein Info
Gene SymbolHMOX2PROTEIN
Chromosome16q13.3
Protein TypeEnzyme
Functionis a constitutively expressed enzyme that catalyzes the degradation of heme into biliverdin, carbon monoxide, and free iron.
GeneCardsHMOX2PROTEIN
Human Protein AtlasHMOX2PROTEIN
N-terminal membrane anchorAnchors to endoplasmic reticulum
Heme-binding pocketContains the catalytic site
Histidine-rich regionPotential metal binding site
C-terminal domainContains heme regulatory motifs (HRMs)
BiliverdinConverted to bilirubin, an antioxidant
Carbon monoxide (CO)Signaling molecule
Free ironRecycled via ferritin storage
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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