| Gene Symbol | HAPLN1 |
| Full Name | Hyaluronan and Proteoglycan Link Protein 1 |
| Aliases | HAPLN1PROTEIN |
| Chromosome | 19q13.12 |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | </b></td><td>Extracellular matrix, secreted</td></tr> |
| Molecular Weight | 40 kDa |
| UniProt ID | P10915 |
| GeneCards | HAPLN1 |
| Human Protein Atlas | HAPLN1 |
| N-terminal domain | Link module that binds hyaluronan |
| Core protein | Central region with multiple glycosylation sites |
| C-terminal domain | Binds to chondroitin sulfate proteoglycans (CSPGs) |
| Link module family | Shares homology with other link proteins (HAPLN2-5) |
| Perineuronal net degradation | Early loss of PNN integrity in AD |
| Associated Diseases | Als, Inflammation, Neuroinflammation, Ptsd |
| KG Connections | 25 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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