| Gene Symbol | GRIP2 |
| Full Name | Glutamate Receptor Interacting Protein 2 |
| Aliases | Page for GRIP2, Page for GRIP2 Protein |
| Chromosome | 3p24.3 |
| Protein Type | Protein |
| Function | is a neuronal scaffolding protein that plays essential roles in synaptic function, plasticity, and trafficking of ionotropic glutamate receptors. |
| Primary Expression | the brain, with high levels in the hippocampus, cortex, and cerebellum—regions critical for learning, memory, and motor coord |
| Molecular Weight | 112.8 kDa |
| Amino Acids | 1112 aa |
| UniProt ID | Search UniProt |
| GeneCards | GRIP2 |
| Human Protein Atlas | GRIP2 |
| PDZ domains 1-2 | Bind to the C-terminal PDZ-binding motifs of AMPA receptor subunits |
| PDZ domains 3-5 | Interact with other scaffolding proteins (GRIP1, PICK1) |
| PDZ domains 6-7 | Connect to additional binding partners and signaling proteins |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!