| Gene Symbol | GP45PROTEIN |
| Full Name | GCLC (Glutamate-Cysteine Ligase Catalytic Subunit) |
| Chromosome | 1q31 |
| Protein Type | Protein |
| Function | is a transmembrane protein tyrosine phosphatase critical for lymphocyte function[@biology2020]. |
| Amino Acids | 047 aa |
| UniProt ID | Search UniProt |
| GeneCards | GP45PROTEIN |
| Human Protein Atlas | GP45PROTEIN |
| Immune cells | T cells, B cells, NK cells, macrophages |
| Brain | Microglia, some neurons, endothelial cells |
| Isoform patterns | Different isoforms innaive vs. memory T cells |
| Development | Regulated expression during hematopoiesis[@ptprc2020] |
| Extracellular domain | Variable due to alternative splicing |
| Single transmembrane domain | Connects to cytoplasmic portion |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!