| Gene Symbol | GFRA3PROTEIN |
| Chromosome | 4p15.2 |
| Protein Type | Receptor |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Molecular Weight | ~45-50 kDa (pre-pro form) |
| Amino Acids | 465 amino acids |
| UniProt ID | Q9Y5R5 |
| NCBI Gene ID | 64054 |
| Ensembl ID | ENSG00000146070 |
| GeneCards | GFRA3PROTEIN |
| Human Protein Atlas | GFRA3PROTEIN |
| Signal peptide (1-21 aa) | N-terminal signal sequence for cotranslational insertion into the endoplasmic reticulum |
| N-terminal domain | Contains the ligand-binding interface |
| Three cysteine-rich domains (CRDs) | Each CRD contains conserved cysteine residues forming disulfide bonds that create the structural framework for artemin binding |
| GPI anchor signal sequence (C-terminus) | Directs post-translational attachment of the GPI moiety, anchoring the protein to the outer leaflet of the plasma membrane |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |
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