| Gene Symbol | GEMIN1 |
| Aliases | GEMIN1 gene in ALS and SMA |
| Chromosome | 6q21 |
| Function | encodes a protein of approximately 282 kDa that serves as a molecular scaffold within the SMN complex. |
| Subcellular Localization | </strong> Nucleus (Cajal bodies), cytoplasm</div> <div class="infobox-row"><st |
| Molecular Weight | 282 kDa |
| Ensembl ID | ENSG00000162992 |
| GeneCards | GEMIN1 |
| Human Protein Atlas | GEMIN1 |
| SMN-Gemin1 Interface | A hydrophobic interaction surface where SMN binds to the N-terminal domain of Gemin-1 |
| Sm Protein Binding Pocket | The WD40 domain contains a binding groove for the Sm proteins |
| Dimerization Interface | Gemin-1 can form homodimers through its coiled-coil regions |
| Associated Diseases | ALS |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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