| Gene Symbol | GAMMASECRETASE |
| Aliases | GAMMASECRETASE |
| Chromosome | 14q24.2 |
| Genes | psen1 (chromosome 14q24.2) and psen2 (chromosome 1q42.13) |
| Size | ~50 kDa; contains 9 transmembrane domains (TMDs) |
| Disease relevance | Over 300 mutations in psen1 and ~50 in psen2 cause familial Alzheimer's Disease, making psen1 the most commonly mutated gene in autosomal dominant AD. |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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