| Gene Symbol | DYNC1I1 |
| Full Name | Cytoplasmic Dynein 1 Intermediate Chain 1 |
| Chromosome | 7p21.1 |
| Function | encodes a critical subunit of the cytoplasmic dynein-1 motor complex, the primary molecular motor responsible for retrograde axonal transport in neurons. |
| Gene Type | Protein coding |
| UniProt ID | Q13418 |
| NCBI Gene ID | 1780 |
| Ensembl ID | ENSG00000111595 |
| OMIM | 617305 |
| GeneCards | DYNC1I1 |
| Human Protein Atlas | DYNC1I1 |
| Acetylation | Lysine acetylation at conserved residues regulates motor activity and microtubule binding Rana et al., 2022. |
| Ubiquitination | DYNC1I1 can be ubiquitinated, targeting it for degradation in pathological states. |
| Associated Diseases | neurodegeneration |
| KG Connections | 13 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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