| Gene Symbol | DYNC1H1 |
| Full Name | Dynein Cytoplasmic 1 Heavy Chain 1 |
| Chromosome | 14q32.31 |
| Function | Dynein transports diverse cargo including mitochondria, endosomes, lysosomes, signaling endosomes, and mRNA granules from the distal axon back toward the cell body (retrograde transport). |
| Primary Expression | Motor neurons, Cerebral cortex, Widespread |
| Molecular Weight | 532 kDa |
| UniProt ID | Q14204 |
| NCBI Gene ID | 1778 |
| Ensembl ID | ENSG00000197958 |
| OMIM | 600112 |
| GeneCards | DYNC1H1 |
| Human Protein Atlas | DYNC1H1 |
| Motor domain (AAA+ ring) | Six AAA+ ATPase modules forming a ring |
| Stalk domain | Long alpha-helix extending from the AAA ring |
| Microtubule-binding domain | At tip of stalk, contacts microtubules |
| Databases | GeneCardsHPASTRING |
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