| Gene Symbol | DOPADECARBOXYLASE |
| Aliases | DOPADECARBOXYLASE |
| Chromosome | 7p12.2 |
| Molecular weight | ~54 kDa |
| Primary structure | 480 amino acids |
| Cofactor requirement | Pyridoxal 5'-phosphate (PLP, vitamin B6) |
| Subunit structure | Homodimeric (active form) |
| Enzyme classification | EC 4.1.1.28 (L-tryptophan decarboxylase) |
| Substantia nigra pars compacta | Dopamine neurons projecting to striatum |
| Ventral tegmental area | Dopamine neurons projecting to cortex and limbic system |
| Raphe nuclei | Serotonin neurons throughout the forebrain |
| Locus coeruleus | Noradrenergic neurons |
| Peripheral tissues | Adrenal medulla, enteric nervous system |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!