| Gene Symbol | DNAJC16 |
| Protein Family | DnaJ/Hsp40 Family |
| Protein Type | Chaperone |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | Cytoplasm, Mitochondria, Endoplasmic Reticulum |
| Molecular Weight | 42 kDa |
| Amino Acids | 382 aa |
| UniProt ID | [Q9H0U4](https://www.uniprot.org/uniprot/Q9H0U4) |
| GeneCards | DNAJC16 |
| Human Protein Atlas | DNAJC16 |
| Hsp70 Stimulation | The J domain stimulates Hsp70 ATP hydrolysis, activating Hsp70 for client protein binding |
| De novo Folding | Assists in the folding of newly synthesized polypeptides |
| Refolding | Helps refold stress-damaged proteins in cooperation with Hsp70/Hsp70 systems |
| Mitochondrial Protein Import | Assists in the folding of imported mitochondrial proteins |
| Misfolded Protein Clearance | Targets damaged mitochondrial proteins for degradation |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!