protein 2,389 words KG: DLGH2PROTEIN
Contents

DLGH2PROTEIN Protein

🔬 Protein Info
Gene SymbolDLGH2PROTEIN
Chromosome8p23.3
Protein TypeScaffold Protein
Functionis a fundamental component of the postsynaptic density, a specialized structure beneath the postsynaptic membrane that contains the machinery for synaptic signaling and plasticity.
Primary Expressionthe brain, with particularly high levels in the hippocampus, olfactory bulb, cerebral cortex, and cerebellum
Amino Acids220 aa
Exons24
GeneCardsDLGH2PROTEIN
Human Protein AtlasDLGH2PROTEIN
TATA boxLocated at position -30 relative to the transcription start site
GC-rich regionsMultiple Sp1 binding sites for basal transcription
Neural-specific enhancersBinding sites for neuron-specific transcription factors including Ngn2 and NeuroD1
Activity-dependent elementsCREB response elements enabling regulation by neuronal activity
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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