| Gene Symbol | CUL4A |
| Full Name | Cullin 4A |
| Chromosome | 13q34 |
| Protein Family | Cullin family |
| Function | encodes a member of the cullin family of proteins that serve as molecular scaffolds for multi-subunit ubiquitin ligase complexes. |
| Molecular Weight | 190 kDa |
| UniProt ID | Q13617 |
| NCBI Gene ID | 8451 |
| Ensembl ID | ENSG00000198242 |
| OMIM | 603137 |
| GeneCards | CUL4A |
| Human Protein Atlas | CUL4A |
| N-terminal Domain | Binds to the substrate recognition receptor DDB1 (DNA Damage Binding Protein 1), which recruits specific substrates for ubiquitination[@scrima2008] |
| Cullin Repeat Domain (CR) | Five repeat motifs that form the elongated helical scaffold structure |
| C-terminal Domain | Contains the RING finger motif that recruits the E2 ubiquitin-conjugating enzyme |
| Associated Diseases | Alzheimer's Disease, Parkinson's Disease, X-linked Mental Retardation, Cockayne Syndrome |
| Databases | GeneCardsHPASTRING |
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