| Gene Symbol | CLN3 |
| Aliases | Batten disease, Battenin |
| Function | encodes a lysosomal/endosomal transmembrane protein that is critical for neuronal function and survival. |
| Subcellular Localization | ** | Lysosomal membrane, Endosomal membrane | |
| Molecular Weight | 48 kDa |
| Amino Acids | 438 aa |
| Ensembl ID | ENSG00000158966 |
| GeneCards | CLN3 |
| Human Protein Atlas | CLN3 |
| Signal peptide | None (initiates at methionine) |
| Transmembrane domains | 6 predicted transmembrane helices |
| N-terminus | Cytosolic |
| C-terminus | Cytosolic |
| Large luminal loop | Contains potential N-linked glycosylation sites |
| N-linked glycosylation | 4-5 potential sites in lumenal loops |
| Associated Diseases | Cancer, Cln3 Disease, Ms, neurodegeneration |
| KG Connections | 69 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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