| Gene Symbol | CDH2 |
| Aliases | CDH2PROTEIN |
| Chromosome | 18q12.1 |
| Function | N-cadherin is widely expressed throughout the nervous system, with particularly high levels in the brain, where it serves as a critical regulator of synaptic connectivity and neural circuit formati... |
| GeneCards | CDH2 |
| Human Protein Atlas | CDH2 |
| Exon 1 | 5' UTR and signal peptide |
| Exons 2-12 | Extracellular cadherin repeats |
| Exon 13 | Transmembrane domain |
| Exons 14-16 | Cytoplasmic domain and 3' UTR |
| Catenin-binding region | Interacts with β-catenin and p120-catenin |
| Phosphorylation sites | Regulatory control of protein function |
| PDZ-binding motif | Enables interaction with scaffolding proteins |
| Hippocampus | High expression in CA1-CA3 pyramidal cell layers and dentate gyrus |
| Cortex | Enriched in layers II-IV and V-VI pyramidal neurons |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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