protein 1,470 words KG: CAV12PROTEIN
Contents

L-type Calcium Channel Protein

🔬 Protein Info
Gene SymbolCAV12PROTEIN
FunctionCav1.2 channels are among the most extensively studied ion channels in the context of Alzheimer's disease (AD) and Parkinson's disease (PD) due to their central role in calcium dysregulation—a hallmar
Subcellular Localizationthe cell membrane. It belongs to the Cav1 (L-type) channel family and is composed of a pore-forming α1C subunit (CACNA1C
Molecular Weight~250 kDa for α1 subunit
GeneCardsCAV12PROTEIN
Human Protein AtlasCAV12PROTEIN
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Related Hypotheses (8)

Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73
Mechanosensitive Ion Channel Reprogramming
Score: 0.70
Lysosomal Calcium Channel Modulation Therapy
Score: 0.70
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.67
Mitochondrial Calcium Buffering Enhancement via MCU Modulati
Score: 0.65
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (11)

Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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