protein 1,527 words KG: ATAXIN1
Contents

Ataxin-1

🔬 Protein Info
Gene SymbolATAXIN1
Protein FamilyAtaxin family
FunctionUnder physiological conditions, Ataxin-1 performs essential functions in neuronal development, transcriptional regulation, and cellular homeostasis.
Subcellular Localizationto the nucleus of neurons, where it exerts its normal physi
Molecular Weight87 kDa
UniProt IDP54253
GeneCardsATAXIN1
Human Protein AtlasATAXIN1
HDAC3 (Histone Deacetylase 3)Modulates gene expression through chromatin remodeling
BCL6A transcriptional repressor involved in immune function and neuronal development[@serra2006]
Wnt/β-catenin signalingThrough interaction with HBP1, Ataxin-1 modulates this developmental pathway
DNA damage responseThe protein localizes to DNA damage foci and participates in repair mechanisms[@chen2024]
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

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