| Gene Symbol | A2AADENOSINERECEPTOR |
| Aliases | A2AADENOSINERECEPTOR |
| Subcellular Localization | **: Plasma membrane, lipid rafts [@ciela2019] |
| Striatal function | A2AR is highly expressed in the striatum where it modulates dopamine D2 receptor (D2R) signaling through heteromeric receptor complexes |
| Motor control | A2AR activation promotes locomotion; antagonism reduces motor inhibition |
| Neuroinflammation | A2AR on microglia and astrocytes modulates inflammatory responses |
| Sleep regulation | A2AR in the basal forebrain promotes wakefulness |
| Cardiovascular | Peripheral A2AR causes vasodilation |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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