disease 1,756 words KG: ent-dise-89c6cf2e
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Prognostic Factors in Corticobasal Syndrome

Disease Info
Short survival (<5 years)Associated with AD-type pathology, early cognitive decline, rapid progression of motor features
Median survival (6-8 years)Typical of pathologically confirmed corticobasal degeneration (CBD)
Long survival (>10 years)Associated with genetic forms (especially GRN mutations), slower initial progression
Respiratory complicationsAspiration pneumonia is the most common cause of death (40-60%)
InfectionOther infections (urinary, respiratory)
Neurological complicationsFall-related injuries, seizures
OtherCardiovascular disease, malignancy (similar to age-matched population)
DatabasesOMIMOrphanetClinicalTrialsPubMed

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