disease 1,757 words KG: ent-dise-bff5e2e4
Contents

Pompe Disease

Disease Info
InheritanceAutosomal recessive
GeneGAA (Acid Alpha-Glucosidase) located on chromosome 17q25.2
MutationsOver 200 pathogenic variants identified in the GAA gene
Enzyme deficiencyAcid alpha-glucosidase (GAA), which normally breaks down lysosomal glycogen
DatabasesOMIMOrphanetClinicalTrialsPubMed

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