Contents

ATP13A2/PARK9 Lysosomal Function Therapies for Parkinson's Disease

🔬 Protein Info

Gene Symbol	ent-gene-f7979b3d
P5-ATPase core	Catalytic domain for ion transport [@schultheis2004]
Lysosomal targeting sequence	Directs protein to lysosome [@kettner2021]
Multiple transmembrane domains	Spans lysosomal membrane [@sousa2019]
Manganese	Accumulation causes oxidative stress [@schneider2020]
Zinc	Disrupted signaling affects autophagy [@fei2024]
Calcium	Impaired buffering affects autophagy regulation [@bussian2018]
KG Connections	3 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

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