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Institution: university-of-rochester
institution
3,292 words
KG: Alzheimer's disease
Contents
university-of-rochester
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Knowledge Graph
Related Hypotheses (14)
Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.70
Reelin-Mediated Cytoskeletal Stabilization Protocol
Score: 0.69
TREM2-mediated microglial tau clearance enhancement
Score: 0.59
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.72
Circadian-Synchronized LRP1 Pathway Activation
Score: 0.71
LRP1-Dependent Tau Uptake Disruption
Score: 0.58
Tau-Independent Microtubule Stabilization via MAP6 Enhanceme
Score: 0.57
TREM2-Dependent Microglial Senescence Transition
Score: 0.95
Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.76
APOE-TREM2 Interaction Modulation
Score: 0.74
TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.69
TREM2-Mediated Selective Aggregate Clearance Pathway
Score: 0.58
Extracellular Vesicle Biogenesis Modulation
Score: 0.56
Show 9 more
Related Analyses (3)
Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · completed
Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Related Experiments (1)
ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
See Also (15)
PPAR Signaling Pathway in Neurodegeneration
mechanism · Pages share 5 hypotheses
Endosomal Sorting Defects in Neurodegeneration
mechanism · Pages share 5 hypotheses
Cerebral Amyloid Angiopathy Pathway in Neurodegeneratio
mechanism · Pages share 5 hypotheses
Neurovascular Unit Dysfunction in Neurodegeneration
mechanism · Pages share 5 hypotheses
Senescent Cell Clearance in Neurodegeneration
mechanism · Pages share 5 hypotheses
RNA-Targeted Therapies in Neurodegeneration
mechanism · Pages share 5 hypotheses
Extracellular Vesicle and Tunneling Nanotube-Mediated S
mechanism · Pages share 5 hypotheses
Cerebral Amyloid Angiopathy in Neurodegeneration
mechanism · Pages share 5 hypotheses
Endosomal-Lysosomal Pathway in Neurodegeneration
mechanism · Pages share 5 hypotheses
Neuroimaging Biomarkers for Neurodegeneration
biomarker · Pages share 4 hypotheses
Novartis Alzheimer's Disease Phase 2 Trial (NCT07094516
clinical · Pages share 4 hypotheses
A Phase 3, Randomised, Double-blinded, Placebo-controll
clinical · Pages share 4 hypotheses
Olfactory Mucosa, Blood and Urine for Identification of
clinical · Pages share 4 hypotheses
Rotigotine and Rivastigmine Combination Therapy for Alz
clinical · Pages share 4 hypotheses
Metabolomic Biomarkers in Neurodegeneration
biomarker · Pages share 4 hypotheses
Show 10 more
Knowledge Graph (12 edges)
DNAJB6
associated_with
Alzheimer's disease
cGAS-STING pathway
associated_with
Alzheimer's disease
gut microbiota
associated_with
Alzheimer's disease
insulin resistance
associated_with
Alzheimer's disease
DRP1
associated_with
Alzheimer's disease
SIRT1
associated_with
Alzheimer's disease
SMPD1
associated_with
Alzheimer's disease
SNCA
associated_with
Alzheimer's disease
LRRK2
associated_with
Alzheimer's disease
senescent microglia
associated_with
Alzheimer's disease
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