gene 663 words KG: WNT8B
Contents

WNT8B Gene

🧬 Gene Info
Gene SymbolWingless-Type MMTV Integration Site Family Member 8B
Chromosome10p26.3
Functionis a gene encoding a secreted signaling protein that plays crucial roles in embryonic development, neuronal differentiation, and adult brain function.
Amino Acids350 aa
Gene TypeProtein Coding
PathwaysWNT, Wnt signaling, Wnt, Wnt pathway
UniProt IDQ9Y5Q2
NCBI Gene ID7479
Ensembl IDENSG00000070193
OMIM605396
N-terminal signal peptideDirects secretion
Wnt domain~350 amino acids, the functional core
Multiple cysteine residuesForm disulfide bonds for proper folding
Lipid modification siteC-terminal palmitoylation essential for signaling
BrainHigh expression in developing and adult brain
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

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