| Gene Symbol | WNT6 |
| Full Name | Wnt Family Member 6 |
| Chromosome | 2q35 |
| Protein Type | Gene |
| Function | is a member of the Wnt family of secreted signaling proteins that plays essential roles in embryonic development, tissue patterning, and adult tissue homeostasis[@wntfamily2023]. |
| Primary Expression | subventricular zone (neural stem cell niche), hippocampus (dentate gyrus), and cortex |
| Amino Acids | 349 aa |
| Pathways | WNT, Wnt, wnt, Wnt Signaling |
| GeneCards | WNT6 |
| Human Protein Atlas | WNT6 |
| Signal peptide | Directs secretion from the cell |
| Wnt domain | Conserved cysteine-rich domain essential for receptor binding |
| Glycosylation sites | Post-translational modifications affecting protein stability |
| Lipid modification | Palmitoleoylation required for secretion and activity |
| Planar Cell Polarity (PCP) | Regulates cell polarity and migration |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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